from 47 agencies. Aggregate cancer risk for U.S. population. Application of Palisade or Palisade plus Tilt increased grain yield at Perkins in 2014 even though there was no lodging. The Congressional Review Act, 5 U.S.C. Lodging at head emergence can cause as little as 30 or as much as 80% yield reduction. with the Chemical Abstracts Service number 95266-40-3. In applying this provision, EPA either retains the default value of 10X, or uses a different additional safety factor when reliable data available to EPA support the choice of a different factor. Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). Contacts. The literature also shows that reduction in lodging is relative to the straw strength of the variety. Upon review of the available information, EPA concludes that these tolerances would be safe. EPA is setting different levels than were proposed based on EPA's analysis of the field trial data using the Organization for Economic Cooperation and Development tolerance calculation procedures. The name " " is approved in China for trinexapac and for trinexapac-ethyl. Trinexapac-ethyl, TMS derivative. The President of the United States issues other types of documents, including but not limited to; memoranda, notices, determinations, letters, messages, and orders. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866, entitled Regulatory Planning and Review (58 FR 51735, October 4, 1993). =;Xb`0[,o DUv publication in the future. 02/28/2023, 205 corresponding official PDF file on govinfo.gov. ).However, the seed yield responses of annual ryegrass (Lolium multiflorum Lam.) Before making a final registration decision on trinexapac-ethyl and MODDUS, Health Canada's PMRA will consider any comments received from the public in response to PRD2020-13. Recommendations may change as further research is conducted and new information is obtained. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials. Compliance with the tolerance levels specified below is to be determined by measuring only the free and conjugated forms of both trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and trinexapac, 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent . Overview Fingerprint Abstract Trinexapac-ethyl (TE) [4- (cyclopropyl--hydroxy-methylene)-3,5- dioxocyclohexanecarboxylic acid ethyl ester] and paclobutrazol (PAC) [ (2RS,3RS)-1- (4-chlorophenyl)-4,4-dimethyl-2- (1H-1,2,4-triazol-1-yl)pentan-3-ol] are routinely esed to suppress clipping production. Soil metabolism of trinexapac-ethyl yields the major metabolite trinexapac, mineralisation to CO. 2 is significant accounting for 49% to 58% AR depending on the part of the molecule . on This action does not involve any technical standards that would require Agency consideration of voluntary consensus standards pursuant to section 12(d) of the National Technology Transfer and Advancement Act (NTTAA) (15 U.S.C. EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. . 1035 0 obj <>stream Palisade did not affect lodging at Perkins in 2013. Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. All Reports; All Sectors . Section 408(b)(2)(C) of FFDCA provides that EPA shall apply an additional tenfold (10X) margin of safety for infants and children in the case of threshold effects to account for prenatal and postnatal toxicity and the completeness of the database on toxicity and exposure unless EPA determines based on reliable data that a different margin of safety will be safe for infants and children. Carefully collect remainder. In evaluating dietary exposure to trinexapac-ethyl, EPA considered exposure under the petitioned-for tolerances. Discharge into the environment must be avoided. This final rule establishes tolerances under section 408(d) of FFDCA in response to petitions submitted to the Agency. on ChemSpider ID 83439. EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. S-4400, One Potomac Yard (South Bldg. That document referenced a summary of the petition prepared by Syngenta Crop Protection, LLC, the registrant, which is available in the docket, http://www.regulations.gov. Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. Compliance with the tolerance levels specified below is to be determined by measuring only the free and conjugated forms of both trinexapac-ethyl, ethyl 4- (cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and trinexapac, 4- (cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent Information about this document as published in the Federal Register. As a result, individuals can be exposed by entering these areas if they have been previously treated. EPA determines whether acute and chronic dietary pesticide exposures are safe by comparing aggregate exposure estimates to the aPAD and cPAD. Product Name: Trinexapac-ethyl: CAS No. on documents in the last year, 121 Pursuant to the Congressional Review Act (5 U.S.C. of the issuing agency. I provided 2013 results in a blog post last year, and this post provides an update including our 2014 findings. Application of Palisade plus Tilt reduced lodging over Palisade alone at Chickasha. The quality of Trinexapac-ethyl 95266-40-3 will be secured by ECHEMI. LOAEL = 357 mg/kg/day, based on elevated serum cholesterol values in females, mucoid feces in females and bloody feces in both sexes, and minimal, focal vacuolation of the dorsal medial hippocampus and/or lateral midbrain in both sexes. There is the potential for incidental oral exposure; however, since there is no toxicological endpoint of concern for that route, a quantitative assessment was not conducted. This regulation establishes tolerances for residues of trinexapac-ethyl in or on multiple commodities which are identified and discussed later in this document. No. Bispyribac-sodium selectively controls annual bluegrass in cool-season turf but efficacy may be influenced by management practices, such as plant growth regulator use.